RHOF and ANKFY1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RHOF	ANKFY1
Description		ras homolog family member F, filopodia associated	ankyrin repeat and FYVE domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Cortex Secretory Granule Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Extracellular Exosome	Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Intracellular Membrane-bounded Organelle Macropinosome Extracellular Exosome
	Molecular Function	GTPase Activity GTP Binding Protein Kinase Binding	Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport
Pathways		Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 31194788 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494 27863252)	Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: ANKFY1	7 interacting genes: ANKRD28 CLK1 EHD1 RAB5A RHOD RHOF SRPK2
Entrez ID		54509	51479
HPRD ID		15246	09717
Ensembl ID		ENSG00000139725	ENSG00000185722
Uniprot IDs		Q9HBH0	B3KPZ0 Q9P2R3
PDB IDs
Enriched GO Terms of Interacting Partners?
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