SEPTIN4 and SNCB

Data Source:
HPRD (in vitro, in vivo)

		SEPTIN4	SNCB
Description		septin 4	synuclein beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Septin Complex Cell Division Site Sperm Annulus	Cytoplasm Cytosol Inclusion Body Neuronal Cell Body Axon Terminus
	Molecular Function	Magnesium Ion Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Transition Metal Ion Binding Cuprous Ion Binding
	Biological Process	Apoptotic Process Spermatogenesis Regulation Of Exocytosis Cell Differentiation Positive Regulation Of Protein Ubiquitination Cellular Protein Localization Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Cytoskeleton-dependent Cytokinesis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Chemical Synaptic Transmission Response To Metal Ion Dopamine Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Synaptic Vesicle Endocytosis Synapse Organization Regulation Of Neuron Death
Pathways			MTF1 activates gene expression
Drugs
Diseases			Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
GWAS
Interacting Genes		9 interacting genes: AREL1 BCL2 PRKN SEPTIN5 SEPTIN8 SNCA SNCAIP SNCB XIAP	13 interacting genes: AKT1 APP CENPT GRK1 GRK5 GRK6 HSPA1A LNX1 MORN4 PLK1 PLK3 SEPTIN4 SNCA
Entrez ID		5414	6620
HPRD ID		04738	03980
Ensembl ID		ENSG00000108387	ENSG00000074317
Uniprot IDs		O43236	G4Y815 G4Y816 Q16143
PDB IDs
Enriched GO Terms of Interacting Partners?
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