PMP22 and SHISAL1

Data Source:
BioGRID (two hybrid)

		PMP22	SHISAL1
Description		peripheral myelin protein 22	shisa like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Synapse	Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chemical Synaptic Transmission Peripheral Nervous System Development Cell Death Bleb Assembly Myelin Assembly
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Allergic rhinitis ( 25085501) Amyotrophic lateral sclerosis ( 29566793) Corneal structure ( 23291589) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		59 interacting genes: APOL3 ARL13B ASGR2 ATP6AP2 C16orf54 CANX CD3G CD53 CD69 CEACAM3 CLDN18 CLDN5 CLDN6 CLEC12B CLEC14A CREB3 CREB3L1 DDX52 EBP EDA EMP1 ERGIC3 FAM209A FCGRT FFAR2 GJA8 GPR42 GPR61 GPRC5D IFNGR2 KCNJ6 KCNN4 KLRC1 LMNA MPZ MS4A7 OPRM1 PDZK1IP1 PEX19 PGRMC2 REEP4 SCN3B SDC4 SHISAL1 SLC18A1 SLC38A1 SMIM3 SPACA1 STOM SYT2 TLCD4 TM4SF18 TM4SF19 TMEM139 TMEM14B TMEM30B TMEM31 TMX1 TSPAN12	28 interacting genes: ALG10 ALG10B ASPH C4orf3 CYB561A3 GIMAP5 GJB2 GPR151 GPR25 GYPC LPAR3 MFF MFSD5 MFSD6 PLPP6 PMP22 SCAMP5 SLC16A13 SLC35B2 SLC38A7 SLC39A7 SLC41A2 SLC52A1 TMEM128 TMEM140 TMEM262 TMEM42 ZFPL1
Entrez ID		5376	85352
HPRD ID		03059	19361
Ensembl ID		ENSG00000109099	ENSG00000138944
Uniprot IDs		A8MU75 Q01453 Q6FH25	Q3SXP7
PDB IDs
Enriched GO Terms of Interacting Partners?
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