SHISAL1 and LPAR3

Data Source:
BioGRID (two hybrid)

		SHISAL1	LPAR3
Description		shisa like 1	lysophosphatidic acid receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Synapse
	Molecular Function	Protein Binding	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity
	Biological Process		Activation Of MAPK Activity G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Regulation Of Metabolic Process Bleb Assembly Positive Regulation Of Collateral Sprouting Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Calcium Ion Transport
Pathways			G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS			Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		28 interacting genes: ALG10 ALG10B ASPH C4orf3 CYB561A3 GIMAP5 GJB2 GPR151 GPR25 GYPC LPAR3 MFF MFSD5 MFSD6 PLPP6 PMP22 SCAMP5 SLC16A13 SLC35B2 SLC38A7 SLC39A7 SLC41A2 SLC52A1 TMEM128 TMEM140 TMEM262 TMEM42 ZFPL1	58 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35C2 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79
Entrez ID		85352	23566
HPRD ID		19361	05486
Ensembl ID		ENSG00000138944	ENSG00000171517
Uniprot IDs		Q3SXP7	Q9UBY5
PDB IDs
Enriched GO Terms of Interacting Partners?
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