PRKAG3 and NGRN

Data Source:
BioGRID (two hybrid)

		PRKAG3	NGRN
Description		protein kinase AMP-activated non-catalytic subunit gamma 3	neugrin, neurite outgrowth associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex	Nucleus Nucleoplasm Mitochondrion Nuclear Body Mitochondrial Membrane Intercellular Bridge Mitotic Spindle
	Molecular Function	Protein Binding ATP Binding AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding	RNA Binding Protein Binding RRNA Binding
	Biological Process	Glycogen Biosynthetic Process Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Cell Cycle Arrest Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Macroautophagy Regulation Of Macroautophagy Intracellular Signal Transduction Cellular Response To Glucose Starvation Regulation Of Catalytic Activity Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction By P53 Class Mediator	Neuron Differentiation Positive Regulation Of Mitochondrial Translation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs		Adenosine phosphate Acetylsalicylic acid Fostamatinib
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol ( 25961943) HDL cholesterol levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Monocyte count ( 32888494) Triglyceride levels ( 32203549)	Multiple sclerosis ( 31604244)
Interacting Genes		6 interacting genes: BRCA1 CRYAB KRTAP19-5 LMCD1 NGRN PRKAA1	4 interacting genes: GTF2H5 PRKAG3 TSC22D2 YOD1
Entrez ID		53632	51335
HPRD ID		16085	14825
Ensembl ID		ENSG00000115592	ENSG00000182768
Uniprot IDs		Q9UGI9	Q9NPE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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