NGRN and PRKAG3

Data Source:
BioGRID (two hybrid)

		NGRN	PRKAG3
Description		neugrin, neurite outgrowth associated	protein kinase AMP-activated non-catalytic subunit gamma 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Body Mitochondrial Membrane Intercellular Bridge Mitotic Spindle	Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex
	Molecular Function	RNA Binding Protein Binding RRNA Binding	Protein Binding ATP Binding AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Neuron Differentiation Positive Regulation Of Mitochondrial Translation	Glycogen Biosynthetic Process Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Cell Cycle Arrest Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Macroautophagy Regulation Of Macroautophagy Intracellular Signal Transduction Cellular Response To Glucose Starvation Regulation Of Catalytic Activity Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Signal Transduction By P53 Class Mediator
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs			Adenosine phosphate Acetylsalicylic acid Fostamatinib
Diseases
GWAS		Multiple sclerosis ( 31604244)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol ( 25961943) HDL cholesterol levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Male-pattern baldness ( 28196072) Monocyte count ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		4 interacting genes: GTF2H5 PRKAG3 TSC22D2 YOD1	6 interacting genes: BRCA1 CRYAB KRTAP19-5 LMCD1 NGRN PRKAA1
Entrez ID		51335	53632
HPRD ID		14825	16085
Ensembl ID		ENSG00000182768	ENSG00000115592
Uniprot IDs		Q9NPE2	Q9UGI9
PDB IDs
Enriched GO Terms of Interacting Partners?
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