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PRKAG3
Description
protein kinase AMP-activated non-catalytic subunit gamma 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nucleotide-activated Protein Kinase Complex
Molecular Function
Protein Binding
ATP Binding
AMP Binding
Protein Kinase Regulator Activity
Protein Kinase Binding
Biological Process
Glycogen Biosynthetic Process
Glycolytic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cell Cycle Arrest
Response To Muscle Activity Involved In Regulation Of Muscle Adaptation
Macroautophagy
Regulation Of Macroautophagy
Intracellular Signal Transduction
Cellular Response To Glucose Starvation
Regulation Of Catalytic Activity
Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol (
25961943
)
HDL cholesterol levels (
32203549
)
Lymphocyte counts (
32888494
)
Lymphocyte percentage of white cells (
32888494
)
Male-pattern baldness (
28196072
)
Monocyte count (
32888494
)
Triglyceride levels (
32203549
)
Interacting Genes
6 interacting genes:
BRCA1
CRYAB
KRTAP19-5
LMCD1
NGRN
PRKAA1
Entrez ID
53632
HPRD ID
16085
Ensembl ID
ENSG00000115592
Uniprot IDs
Q9UGI9
PDB IDs
Enriched GO Terms of Interacting Partners
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