NGRN and YOD1

Data Source:
BioGRID (two hybrid)

		NGRN	YOD1
Description		neugrin, neurite outgrowth associated	YOD1 deubiquitinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Body Mitochondrial Membrane Intercellular Bridge Mitotic Spindle	Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding RRNA Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Ubiquitin Protein Ligase Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Neuron Differentiation Positive Regulation Of Mitochondrial Translation	Macroautophagy Protein Deubiquitination Protein Phosphopantetheinylation Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Protein K29-linked Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein K27-linked Deubiquitination Protein K33-linked Deubiquitination
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Systolic blood pressure ( 28234671)
Interacting Genes		4 interacting genes: GTF2H5 PRKAG3 TSC22D2 YOD1	30 interacting genes: BIRC3 DAZAP2 DDIT4L FAM168A INCA1 LMO2 MKRN1 NEDD4 NGRN PLEKHB2 PSMA7 RFC2 RIPK1 RNF216 SHARPIN SNCA SPART TP53BP2 TRAF6 TRIM54 TRIM55 TRIM63 TRIM8 UBC UBE3A UBXN6 USP15 USP21 VCP ZFP57
Entrez ID		51335	55432
HPRD ID		14825	10312
Ensembl ID		ENSG00000182768	ENSG00000180667
Uniprot IDs		Q9NPE2	Q5VVQ6
PDB IDs			4BOQ 4BOS 4BOZ
Enriched GO Terms of Interacting Partners?
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