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PLXNA1 and RND1
Data Source:
HPRD
(in vitro)
PLXNA1
RND1
Description
plexin A1
Rho family GTPase 1
Image
No pdb structure
GO Annotations
Cellular Component
Semaphorin Receptor Complex
Nucleoplasm
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Extracellular Exosome
Cytosol
Cytoskeleton
Plasma Membrane
Adherens Junction
Cell Cortex
Actin Cytoskeleton
Cytoplasmic Vesicle
Cell Projection
Intracellular Membrane-bounded Organelle
Molecular Function
Semaphorin Receptor Activity
Signaling Receptor Activity
GTPase Activity
Signaling Receptor Binding
Protein Binding
GTP Binding
Protein Kinase Binding
Biological Process
Negative Regulation Of Cell Adhesion
Multicellular Organism Development
Regulation Of Cell Shape
Regulation Of Smooth Muscle Cell Migration
Regulation Of Cell Migration
Regulation Of GTPase Activity
Positive Regulation Of Axonogenesis
Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching
Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Neuron Projection Extension
Actin Filament Organization
Negative Regulation Of Cell Adhesion
Establishment Or Maintenance Of Cell Polarity
Small GTPase Mediated Signal Transduction
Regulation Of Cell Shape
Neuron Remodeling
Cell Migration
Cortical Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Pathways
Sema3A PAK dependent Axon repulsion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
CRMPs in Sema3A signaling
CRMPs in Sema3A signaling
Other semaphorin interactions
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
Sema4D mediated inhibition of cell attachment and migration
Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Alcoholic chronic pancreatitis (
28754779
)
Blood protein levels (
30072576
29875488
)
Platelet count (
32888494
)
Refractive error (
32231278
)
Systolic blood pressure (
31469255
)
Weight (
28552196
)
Whole-brain volume (
21116278
)
Bipolar disorder (
21926972
)
Interacting Genes
9 interacting genes:
AKT1
FES
L1CAM
NRP1
NRP2
PLXNB1
RHOD
RND1
SEMA6D
23 interacting genes:
ARFIP2
ARHGAP5
CCNI
COPS2
CREB3L2
EEF1A1
FRS2
FRS3
GPX8
GRB7
ID3
MYH7
MYOM3
MYZAP
NEDD1
PAIP1
PDE6D
PLXNA1
PLXNB1
PLXNB2
RAI14
UBXN11
ZNF212
Entrez ID
5361
27289
HPRD ID
11868
12357
Ensembl ID
ENSG00000114554
ENSG00000172602
Uniprot IDs
Q9UIW2
Q92730
PDB IDs
2CLS
2REX
3Q3J
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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