PLRG1 and MIRLET7A2

Data Source:
BioGRID (unspecified method)

		PLRG1	MIRLET7A2
Description		pleiotropic regulator 1	microRNA let-7a-2
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Fibrillar Center Nucleus Nucleoplasm DNA Replication Factor A Complex Nuclear Speck Nuclear Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Localization To Nucleus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	Gene Silencing By MiRNA
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Fibrinogen ( 21757653) Fibrinogen levels ( 29403010 28107422)
Interacting Genes		14 interacting genes: APP CDC5L CNN1 HNRNPM MIR106B MIR205 MIR93 MIRLET7A2 MIRLET7E MIRLET7G MIRLET7I MX1 SF3B1 ZSCAN1	95 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC40 CDC5L CHERP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PLOD1 PLRG1 PRMT1 PTBP1 PTCD3 PUM1 PUM2 QARS1 RARS1 RBM14 RBM17 RBM4 RTCB SAFB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR
Entrez ID		5356	406882
HPRD ID		16181
Ensembl ID		ENSG00000171566	ENSG00000198975
Uniprot IDs		O43660
PDB IDs		4YVD 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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