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MIRLET7A2 and LARS1
Data Source:
BioGRID
(unspecified method)
MIRLET7A2
LARS1
Description
microRNA let-7a-2
leucyl-tRNA synthetase 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Lysosome
Endoplasmic Reticulum
Cytosol
Endomembrane System
Nuclear Body
Aminoacyl-tRNA Synthetase Multienzyme Complex
Molecular Function
Aminoacyl-tRNA Editing Activity
Glutamine-tRNA Ligase Activity
Leucine-tRNA Ligase Activity
GTPase Activator Activity
Protein Binding
ATP Binding
Biological Process
Gene Silencing By MiRNA
TRNA Aminoacylation For Protein Translation
Glutaminyl-tRNA Aminoacylation
Leucyl-tRNA Aminoacylation
Regulation Of Cell Size
Positive Regulation Of TOR Signaling
Cellular Response To Amino Acid Starvation
Positive Regulation Of GTPase Activity
Cellular Response To Amino Acid Stimulus
Cellular Response To Leucine
Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Positive Regulation Of TORC1 Signaling
Cellular Response To Leucine Starvation
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Leucine
Diseases
GWAS
Interacting Genes
95 interacting genes:
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC40
CDC5L
CHERP
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
P3H1
PDCD11
PGAM5
PLOD1
PLRG1
PRMT1
PTBP1
PTCD3
PUM1
PUM2
QARS1
RARS1
RBM14
RBM17
RBM4
RTCB
SAFB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
55 interacting genes:
CDC42
EEF1G
ESR1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR15A
MIR15B
MIR17
MIR18A
MIR18B
MIR199A1
MIR19B1
MIR19B2
MIR200A
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR25
MIR29A
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
SUMO2
Entrez ID
406882
51520
HPRD ID
01042
Ensembl ID
ENSG00000198975
ENSG00000133706
Uniprot IDs
A0A6I8PL42
B4DER1
B4E266
Q9P2J5
PDB IDs
2WFD
6LPF
6LR6
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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