PLP2 and EBP

Data Source:
BioGRID (two hybrid)

		PLP2	EBP
Description		proteolipid protein 2	EBP cholestenol delta-isomerase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding	C-8 Sterol Isomerase Activity Steroid Delta-isomerase Activity Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Cholestenol Delta-isomerase Activity
	Biological Process	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport	Skeletal System Development Cholesterol Biosynthetic Process Cholesterol Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol Xenobiotic Transport
Pathways			Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs			Tamoxifen
Diseases
GWAS		Platelet distribution width ( 32888494)
Interacting Genes		74 interacting genes: AQP2 AQP3 AQP8 ARFIP2 ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC14A2 SLC18A1 SLC2A13 SLC35C2 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1	171 interacting genes: ABHD16A ANKRD46 APP AQP6 ARL13B ARL6IP6 ARV1 ATP13A1 BMP10 BNIP3 BTN2A2 C2 C2CD2L C4orf3 C5 C5orf46 CCDC167 CCL4L2 CD40 CD69 CD81 CDIPT CHODL CLDND2 CREB3 CREB3L1 CYB561 CYB5B CYP4F2 DEFB103A DEFB103B DEFB127 DNAJC30 EBPL EMC6 EMP1 ERG28 ERGIC3 ESRRG FA2H FAM209A FAXDC2 FCER1G FETUB FIS1 FKBP8 FUNDC2 FXYD3 FXYD6 GIMAP1 GIMAP5 GJB2 GJB6 GLP1R GOSR2 GPR152 HMOX2 HSD17B13 IER3IP1 INSIG2 JAGN1 LDLRAD1 LEMD1 LPCAT2 LRP10 LRRC59 LTC4S MFSD6 MITF MMP14 MS4A13 MTNR1B NAT8 NDUFA3 NDUFB11 NEU1 NINJ1 NINJ2 NKG7 ODF4 ORMDL1 ORMDL2 ORMDL3 OTOP3 PLLP PLP2 PLPP6 PMP22 PNLIPRP1 PTPN9 PVR RNF152 RTP2 RUSF1 SACM1L SCAMP4 SEC22B SERP1 SERP2 SFXN5 SLC35G1 SLC3A2 SLC41A2 SMAGP SMCO4 SMIM1 SMIM3 SNORC STX12 STX1B STX5 STX6 STX7 STX8 SYNGR1 SYNJ2BP SYS1 TBC1D20 THBD TIMM23 TLCD1 TLCD4 TMBIM6 TMEM100 TMEM11 TMEM120B TMEM140 TMEM147 TMEM14B TMEM14C TMEM167B TMEM199 TMEM203 TMEM208 TMEM218 TMEM222 TMEM229B TMEM239 TMEM242 TMEM243 TMEM254 TMEM31 TMEM42 TMEM51 TMEM60 TMEM65 TMEM86A TMEM86B TMEM97 TMIE TRARG1 TREX1 TSNARE1 TSPO2 UBE2J1 UBIAD1 UNC50 UNC93B1 USE1 VAMP1 VAMP2 VAMP3 VAMP4 VAPA VAPB YIF1A YIPF1 YIPF4 YIPF6 ZDHHC24 ZFPL1
Entrez ID		5355	10682
HPRD ID		02121	02192
Ensembl ID		ENSG00000102007	ENSG00000147155
Uniprot IDs		A0A024QYW3 Q04941	A0A024QYX0 Q15125
PDB IDs			6OHT 6OHU
Enriched GO Terms of Interacting Partners?
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