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EBP and SACM1L
Data Source:
BioGRID
(two hybrid)
EBP
SACM1L
Description
EBP cholestenol delta-isomerase
SAC1 like phosphatidylinositide phosphatase
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Cytoplasmic Vesicle
Golgi Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Integral Component Of Membrane
Endoplasmic Reticulum-plasma Membrane Contact Site
Molecular Function
C-8 Sterol Isomerase Activity
Steroid Delta-isomerase Activity
Transmembrane Signaling Receptor Activity
Protein Binding
Identical Protein Binding
Xenobiotic Transmembrane Transporter Activity
Cholestenol Delta-isomerase Activity
Phosphatidylinositol-3-phosphatase Activity
Protein Binding
Phosphatase Activity
Phosphatidylinositol Phosphate 4-phosphatase Activity
Phosphatidylinositol-4-phosphate Phosphatase Activity
Biological Process
Skeletal System Development
Cholesterol Biosynthetic Process
Cholesterol Metabolic Process
Sterol Biosynthetic Process
Cholesterol Biosynthetic Process Via Desmosterol
Cholesterol Biosynthetic Process Via Lathosterol
Xenobiotic Transport
Phosphatidylinositol Biosynthetic Process
Phosphatidylinositol Dephosphorylation
Pathways
Cholesterol biosynthesis via desmosterol
Cholesterol biosynthesis via lathosterol
Synthesis of PIPs at the ER membrane
Synthesis of PIPs at the Golgi membrane
Drugs
Tamoxifen
Diseases
GWAS
Acne (severe) (
24927181
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Response to anti-depressant treatment in major depressive disorder (
22041458
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
171 interacting genes:
ABHD16A
ANKRD46
APP
AQP6
ARL13B
ARL6IP6
ARV1
ATP13A1
BMP10
BNIP3
BTN2A2
C2
C2CD2L
C4orf3
C5
C5orf46
CCDC167
CCL4L2
CD40
CD69
CD81
CDIPT
CHODL
CLDND2
CREB3
CREB3L1
CYB561
CYB5B
CYP4F2
DEFB103A
DEFB103B
DEFB127
DNAJC30
EBPL
EMC6
EMP1
ERG28
ERGIC3
ESRRG
FA2H
FAM209A
FAXDC2
FCER1G
FETUB
FIS1
FKBP8
FUNDC2
FXYD3
FXYD6
GIMAP1
GIMAP5
GJB2
GJB6
GLP1R
GOSR2
GPR152
HMOX2
HSD17B13
IER3IP1
INSIG2
JAGN1
LDLRAD1
LEMD1
LPCAT2
LRP10
LRRC59
LTC4S
MFSD6
MITF
MMP14
MS4A13
MTNR1B
NAT8
NDUFA3
NDUFB11
NEU1
NINJ1
NINJ2
NKG7
ODF4
ORMDL1
ORMDL2
ORMDL3
OTOP3
PLLP
PLP2
PLPP6
PMP22
PNLIPRP1
PTPN9
PVR
RNF152
RTP2
RUSF1
SACM1L
SCAMP4
SEC22B
SERP1
SERP2
SFXN5
SLC35G1
SLC3A2
SLC41A2
SMAGP
SMCO4
SMIM1
SMIM3
SNORC
STX12
STX1B
STX5
STX6
STX7
STX8
SYNGR1
SYNJ2BP
SYS1
TBC1D20
THBD
TIMM23
TLCD1
TLCD4
TMBIM6
TMEM100
TMEM11
TMEM120B
TMEM140
TMEM147
TMEM14B
TMEM14C
TMEM167B
TMEM199
TMEM203
TMEM208
TMEM218
TMEM222
TMEM229B
TMEM239
TMEM242
TMEM243
TMEM254
TMEM31
TMEM42
TMEM51
TMEM60
TMEM65
TMEM86A
TMEM86B
TMEM97
TMIE
TRARG1
TREX1
TSNARE1
TSPO2
UBE2J1
UBIAD1
UNC50
UNC93B1
USE1
VAMP1
VAMP2
VAMP3
VAMP4
VAPA
VAPB
YIF1A
YIPF1
YIPF4
YIPF6
ZDHHC24
ZFPL1
35 interacting genes:
ACKR2
AQP6
ARL13B
CD79A
COPA
COPB2
COPG1
CREB3
CREB3L1
DHRS7
EBP
FFAR2
FMO3
GPR151
GPR152
HSD17B13
JAGN1
LMNA
MFF
MFSD14B
MTERF2
ODF4
PRKCA
RNF19B
RTN3
SCN3B
SLC10A1
SLC10A6
SLC35A5
SLC35C2
SLC7A1
TMEM167B
TMX2
VEZT
ZFYVE27
Entrez ID
10682
22908
HPRD ID
02192
07587
Ensembl ID
ENSG00000147155
ENSG00000211456
Uniprot IDs
A0A024QYX0
Q15125
B4DVV3
E9PGZ4
Q9NTJ5
PDB IDs
6OHT
6OHU
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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