EBP and TMEM199

Data Source:
BioGRID (two hybrid)

		EBP	TMEM199
Description		EBP cholestenol delta-isomerase	transmembrane protein 199
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Cytoplasmic Vesicle	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	C-8 Sterol Isomerase Activity Steroid Delta-isomerase Activity Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding Xenobiotic Transmembrane Transporter Activity Cholestenol Delta-isomerase Activity	Protein Binding
	Biological Process	Skeletal System Development Cholesterol Biosynthetic Process Cholesterol Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol Xenobiotic Transport	Cellular Iron Ion Homeostasis Lysosomal Lumen Acidification Cellular Response To Increased Oxygen Levels Vacuolar Proton-transporting V-type ATPase Complex Assembly Lysosomal Protein Catabolic Process
Pathways		Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol
Drugs		Tamoxifen
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Blood protein levels ( 29875488) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Osteoprotegerin levels ( 25080503) Triglyceride levels ( 32203549)
Interacting Genes		171 interacting genes: ABHD16A ANKRD46 APP AQP6 ARL13B ARL6IP6 ARV1 ATP13A1 BMP10 BNIP3 BTN2A2 C2 C2CD2L C4orf3 C5 C5orf46 CCDC167 CCL4L2 CD40 CD69 CD81 CDIPT CHODL CLDND2 CREB3 CREB3L1 CYB561 CYB5B CYP4F2 DEFB103A DEFB103B DEFB127 DNAJC30 EBPL EMC6 EMP1 ERG28 ERGIC3 ESRRG FA2H FAM209A FAXDC2 FCER1G FETUB FIS1 FKBP8 FUNDC2 FXYD3 FXYD6 GIMAP1 GIMAP5 GJB2 GJB6 GLP1R GOSR2 GPR152 HMOX2 HSD17B13 IER3IP1 INSIG2 JAGN1 LDLRAD1 LEMD1 LPCAT2 LRP10 LRRC59 LTC4S MFSD6 MITF MMP14 MS4A13 MTNR1B NAT8 NDUFA3 NDUFB11 NEU1 NINJ1 NINJ2 NKG7 ODF4 ORMDL1 ORMDL2 ORMDL3 OTOP3 PLLP PLP2 PLPP6 PMP22 PNLIPRP1 PTPN9 PVR RNF152 RTP2 RUSF1 SACM1L SCAMP4 SEC22B SERP1 SERP2 SFXN5 SLC35G1 SLC3A2 SLC41A2 SMAGP SMCO4 SMIM1 SMIM3 SNORC STX12 STX1B STX5 STX6 STX7 STX8 SYNGR1 SYNJ2BP SYS1 TBC1D20 THBD TIMM23 TLCD1 TLCD4 TMBIM6 TMEM100 TMEM11 TMEM120B TMEM140 TMEM147 TMEM14B TMEM14C TMEM167B TMEM199 TMEM203 TMEM208 TMEM218 TMEM222 TMEM229B TMEM239 TMEM242 TMEM243 TMEM254 TMEM31 TMEM42 TMEM51 TMEM60 TMEM65 TMEM86A TMEM86B TMEM97 TMIE TRARG1 TREX1 TSNARE1 TSPO2 UBE2J1 UBIAD1 UNC50 UNC93B1 USE1 VAMP1 VAMP2 VAMP3 VAMP4 VAPA VAPB YIF1A YIPF1 YIPF4 YIPF6 ZDHHC24 ZFPL1	17 interacting genes: AQP6 BIK CCR2 CD300A EBP ELOVL4 ERLIN1 IFNGR2 JAGN1 KASH5 LMNA REEP4 SLC10A4 STX1A STX4 TIMMDC1 TMEM14B
Entrez ID		10682	147007
HPRD ID		02192	12679
Ensembl ID		ENSG00000147155	ENSG00000244045
Uniprot IDs		A0A024QYX0 Q15125	Q8N511
PDB IDs		6OHT 6OHU
Enriched GO Terms of Interacting Partners?
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