PLP2 and CRB3

Data Source:
BioGRID (two hybrid)

		PLP2	CRB3
Description		proteolipid protein 2	crumbs cell polarity complex component 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Extracellular Exosome
	Molecular Function	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding	Protein Binding SH3 Domain Binding Protein Domain Specific Binding
	Biological Process	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport	Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Positive Regulation Of Cell Junction Assembly
Pathways			Tight junction interactions
Drugs
Diseases
GWAS		Platelet distribution width ( 32888494)
Interacting Genes		74 interacting genes: AQP2 AQP3 AQP8 ARFIP2 ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC14A2 SLC18A1 SLC2A13 SLC35C2 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1	28 interacting genes: ANKRD46 BCL2L13 BET1 FUNDC2 HMOX1 HMOX2 NDUFA3 PALS1 PARD6A PATJ PLLP PLP2 PSENEN PSMA3 RABAC1 SERF1A SERF1B SERP1 SLC39A9 STX5 TECR TMEM222 TREX1 UBIAD1 VAMP1 VTI1B WDR83 YIPF6
Entrez ID		5355	92359
HPRD ID		02121	16749
Ensembl ID		ENSG00000102007	ENSG00000130545
Uniprot IDs		A0A024QYW3 Q04941	Q9BUF7
PDB IDs			5I7Z
Enriched GO Terms of Interacting Partners?
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