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CASP4 and ELF4
Data Source:
BioGRID
(two hybrid)
CASP4
ELF4
Description
caspase 4
E74 like ETS transcription factor 4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Protein-containing Complex
IPAF Inflammasome Complex
NLRP3 Inflammasome Complex
AIM2 Inflammasome Complex
Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PML Body
Molecular Function
Cysteine-type Endopeptidase Activity
Protein Binding
CARD Domain Binding
Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Proteolysis
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Inflammatory Response
Protein Autoprocessing
Regulation Of Apoptotic Process
Innate Immune Response
Regulation Of Inflammatory Response
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pyroptosis
Intrinsic Apoptotic Signaling Pathway
Execution Phase Of Apoptosis
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Cellular Response To Amyloid-beta
Natural Killer Cell Proliferation
NK T Cell Proliferation
Regulation Of Transcription By RNA Polymerase II
Cell Differentiation
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
NOD1/2 Signaling Pathway
Drugs
Incadronic acid
Diseases
GWAS
Major depressive disorder (
29317602
)
Bipolar disorder (
31043756
)
Interacting Genes
16 interacting genes:
APAF1
APP
CASP10
CASP14
CASP3
CASP8
DSP
ELF4
IL18
IL1B
IL37
MYH9
NOD1
PLA2G4A
PSEN1
SERPINB9
9 interacting genes:
CASP4
FBXO4
FBXO7
NPM1
PML
RUNX1
SET
SKP2
UBB
Entrez ID
837
2000
HPRD ID
04047
06499
Ensembl ID
ENSG00000196954
ENSG00000102034
Uniprot IDs
P49662
Q99607
PDB IDs
6KMZ
6NRY
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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