PGD and GBE1

Data Source:
HPRD (two hybrid)

		PGD	GBE1
Description		phosphogluconate dehydrogenase	1,4-alpha-glucan branching enzyme 1
Image
GO Annotations	Cellular Component	Nucleus Cytosol Extracellular Exosome	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Phosphogluconate Dehydrogenase (decarboxylating) Activity NADP Binding	1,4-alpha-glucan Branching Enzyme Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Protein Binding Carbohydrate Binding Cation Binding 1,4-alpha-glucan Branching Enzyme Activity (using A Glucosylated Glycogenin As Primer For Glycogen Synthesis)
	Biological Process	Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch Pentose Biosynthetic Process D-gluconate Catabolic Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Biosynthetic Process Generation Of Precursor Metabolites And Energy Negative Regulation Of Neuron Apoptotic Process
Pathways		Pentose phosphate pathway	Glycogen synthesis Glycogen storage disease type IV (GBE1)
Drugs		Gadopentetic acid Dacarbazine Ketotifen 6-phospho-D-gluconic acid Nicotinamide 8-bromo-adenine dinucleotide phosphate
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS		Hemoglobin ( 32888494) Hepatocellular carcinoma ( 20676096) Metabolite levels ( 23823483)	Adult body size ( 32376654) Body mass index ( 25673413) Cadmium levels ( 26025379) Chronotype ( 30696823) Extraversion ( 27918536) Hand grip strength ( 29691431) Intraocular pressure ( 31798171) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Iron status biomarkers (transferrin saturation) ( 28334935) Lead levels in blood ( 25820613) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Meat-related diet ( 32066663) Photic sneeze reflex ( 30899065) Processed meat consumption ( 32066663) Risk-taking tendency (4-domain principal component model) ( 30643258) Waist circumference ( 25673412)
Interacting Genes		6 interacting genes: CDC42 CDK4 GBE1 LINC01554 LSM8 TERF1	5 interacting genes: EPHB3 PGD PRMT6 RIPK3 TRDMT1
Entrez ID		5226	2632
HPRD ID		01391	01985
Ensembl ID		ENSG00000142657	ENSG00000114480
Uniprot IDs		B4E2U0 P52209	Q04446 Q59ET0
PDB IDs		2JKV 4GWG 4GWK 5UQ9	4BZY 5CLT 5CLW
Enriched GO Terms of Interacting Partners?
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