Description |
WW domain containing oxidoreductase |
trichoplein keratin filament binding |
Image |
|
No pdb structure |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
- Alzheimer's disease (late onset) ( 30820047)
- Anorexia nervosa ( 23568457)
- Bipolar disorder (body mass index interaction) ( 24322204)
- Brain morphology (MOSTest) ( 32665545)
- Brain volume in infants (white matter) ( 28763065)
- Cardiac structure and function ( 19584346)
- Clozapine-induced cytotoxicity ( 25656473)
- Colorectal cancer ( 30529582 29228715)
- Daytime sleep phenotypes ( 27126917)
- Diffusing capacity of carbon monoxide ( 30694715)
- Early-onset Parkinson's disease ( 28256260)
- Eosinophil counts ( 32888494)
- Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
- Familial squamous cell lung carcinoma ( 29924316)
- FEV1 ( 30804560)
- Gut microbiota relative abundance (Faecalibacterium) ( 33208821)
- Hematocrit ( 32888494)
- Hemoglobin ( 32888494)
- Hip shape (DXA scan) ( 30320955)
- Idiopathic dilated cardiomyopathy ( 29495422)
- Lung function (forced vital capacity) ( 24929828)
- Lung function (FVC) ( 30804560)
- Lymphocyte counts ( 32888494)
- Macular thickness ( 30535121)
- Metabolite levels ( 23823483)
- Metabolite levels (5-HIAA) ( 23319000)
- Molybdenum levels ( 26025379)
- Monocyte count ( 32888494)
- Multiple sclerosis ( 31604244 24076602)
- Obesity ( 21552555)
- Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
- Peak expiratory flow ( 30804560)
- Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
- Platelet count ( 32888494)
- Plateletcrit ( 32888494)
- Post bronchodilator FEV1/FVC ratio ( 26634245)
- Pulmonary function ( 21946350)
- Pulmonary function (smoking interaction) ( 23284291)
- Radiation response ( 20923822)
- Red blood cell count ( 32888494)
- Refractive error ( 32231278)
- Response to amphetamines ( 22952603)
- Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309)
- Response to fenofibrate (HDL cholesterol levels) ( 27002377)
- Serum thyroid-stimulating hormone levels ( 25436638)
- Serum uric acid levels in response to allopurinol in gout ( 25676789)
- Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
- Systemic juvenile idiopathic arthritis ( 27927641)
- Type 2 diabetes ( 22158537)
- Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
|
- Bipolar disorder ( 31043756)
- Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980)
- Metabolite levels (MHPG) ( 23319000)
- Myocardial infarction ( 30226566)
- Platelet count ( 32888494)
- Pulse pressure ( 27841878)
- Systolic blood pressure ( 27841878)
|
Interacting Genes |
116 interacting genes:
ABHD11
ABI2
ACAT2
ACY1
ADRA2C
ANAPC11
ANXA11
APBB2
ARRDC3
C10orf55
C11orf87
C19orf54
CCDC24
CEACAM6
CLNK
CNNM3
CPSF2
CPSF6
CPSF7
CREB5
CSNK2B
CTAG1A
CTAG1B
CTDSP1
DAZAP2
DMRT3
ENKD1
ERBB4
EZR
FAM214B
FAM222B
FEM1A
FIP1L1
FOXD4L1
FOXI1
FRS3
GCM2
GEM
GLIS2
GNE
HNRNPK
HOXA1
HOXC8
HSPB2
HSPB2-C11orf52
HYAL2
IFIT2
INCA1
KLHDC7B
KLHL38
KRT3
KRT34
KRT75
KRTAP11-1
LASP1
LATS1
LITAF
LMO3
MAPK8
MED25
MKRN3
MYG1
MYOZ1
MYOZ2
NEDD9
NUDT21
OLIG3
OTX1
PATL1
PATZ1
PAX9
PBX4
PEF1
PITX2
PLAC8
PLEKHN1
PLSCR3
PPP1R32
PSMB8
RAMAC
RUSC1
SAXO1
SCAMP3
SEC23IP
SF3B3
SH2D4A
SHC3
SLC15A2
SMAD4
SMR3A
SNRPC
SRC
TCERG1
TCHP
TEKT3
TEX37
TFAP2C
TFG
TNK2
TP53
TP73
TRIM69
TSGA10IP
UBB
UFSP1
VENTX
VEZF1
VPS37C
WDR33
WIPF2
YPEL3
ZBTB32
ZIC1
ZNF135
ZNF414
ZNF581
|
52 interacting genes:
ATPAF2
BCAS2
C21orf91
CBY2
CCDC125
CCDC13
CCDC172
CCDC85B
CDR2
CDR2L
DMAP1
DYDC1
EIF4ENIF1
HOOK2
ID2
IFFO1
IKZF3
KCTD17
KIAA0753
KRT14
KRT15
KRT16
KRT18
KRT19
KRT24
KRT32
KRT34
KRT35
KRT40
KRT5
KRT6A
KRT75
KRT8
MIIP
MIPOL1
MKRN3
MTUS2
NAB2
NDOR1
NME7
NUP54
PRDM16
PSMB5
RABGEF1
RUSC1
TEX11
TRIM27
TRIM54
USHBP1
VIM
WWOX
ZIM2
|
Entrez ID |
51741 |
84260 |
HPRD ID |
05501 |
14403 |
Ensembl ID |
ENSG00000186153
|
ENSG00000139437
|
Uniprot IDs |
A0A411HBC7
Q9NZC7
|
A0A024RBM9
Q9BT92
|
PDB IDs |
1WMV
|
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|