TRAPPC2L and TRAPPC6A

Data Source:
BioGRID (two hybrid)

		TRAPPC2L	TRAPPC6A
Description		trafficking protein particle complex subunit 2L	trafficking protein particle complex subunit 6A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Carotid intima media thickness (mean) ( 31801372) Hair color ( 26926045)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		27 interacting genes: APP BLZF1 BSDC1 C11orf68 CEP57L1 GPANK1 LCN2 LHX2 LMO3 MEI4 MEOX1 MEOX2 POLR2G RABEP1 REL REPS1 SSX2 SSX2B TCF4 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRIP6 YPEL3 ZBTB42	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		51693	79090
HPRD ID		13711	14503
Ensembl ID		ENSG00000167515	ENSG00000007255
Uniprot IDs		A0A0B4J294 H3BQQ8 H3BUK6 Q9UL33	B7TZ90 O75865
PDB IDs			2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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