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CPSF3 and FAM107A
Data Source:
BioGRID
(two hybrid)
CPSF3
FAM107A
Description
cleavage and polyadenylation specific factor 3
family with sequence similarity 107 member A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Stress Fiber
Nucleus
Cytoplasm
Focal Adhesion
Actin Cytoskeleton
Nuclear Speck
Ruffle Membrane
Neuron Projection
Synapse
Molecular Function
RNA Binding
Endoribonuclease Activity
Protein Binding
5'-3' Exonuclease Activity
Metal Ion Binding
Molecular_function
Actin Binding
Protein Binding
Biological Process
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Cleavage
MRNA 3'-end Processing By Stem-loop Binding And Cleavage
MRNA Export From Nucleus
MRNA 3'-end Processing
RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Regulation Of Cell Growth
Cell Cycle
Actin Filament Polymerization
Positive Regulation Of Cell Migration
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Stability
Cellular Response To Nutrient Levels
Regulation Of Actin Cytoskeleton Organization
Cognition
Actin Filament Bundle Assembly
Negative Regulation Of Focal Adhesion Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Glucocorticoid Stimulus
Negative Regulation Of Long-term Synaptic Potentiation
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Night sleep phenotypes (
27126917
)
Interacting Genes
9 interacting genes:
CLP1
FAM107A
HSPB1
MIR19A
MIR19B1
MIR92A2
PAPOLA
POLR2A
YWHAG
58 interacting genes:
AGMAT
APPBP2
AUH
AZI2
BEGAIN
BIRC8
CALCOCO2
CANX
CCDC125
CCDC136
CCDC57
CCDC85B
CPSF3
DAPK1
EFEMP2
EFHC2
EIF4A1
ESRRG
FKBP6
FSD2
GFM2
GOLGA6L9
HFM1
HOOK2
HSF2BP
HSPA14
HSPD1
HTRA1
IQUB
ITPRID2
KRT15
KRT19
KRT27
KRT40
KRTAP4-12
LDOC1
LZTS2
MEIOB
MID2
MTREX
MTUS2
NEXN
NFKBID
NINL
PLSCR1
PNMA1
POMP
PSMD6
RAB18
RINT1
RNLS
SPATA22
TADA2A
TRAF2
TRIM37
USHBP1
VIM
WDR47
Entrez ID
51692
11170
HPRD ID
05825
09753
Ensembl ID
ENSG00000119203
ENSG00000168309
Uniprot IDs
G5E9W3
Q9UKF6
A0A024R327
O95990
Q6IAM1
PDB IDs
2I7T
2I7V
6M8Q
6V4X
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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