PDGFRL and CTSV

Data Source:
BioGRID (two hybrid)

		PDGFRL	CTSV
Description		platelet derived growth factor receptor like	cathepsin V
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Extracellular Region	Extracellular Region Extracellular Space Lysosome Lysosomal Lumen
	Molecular Function	Platelet Activating Factor Receptor Activity Platelet-derived Growth Factor Beta-receptor Activity	Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Biological_process Platelet-derived Growth Factor Receptor-beta Signaling Pathway	Immune Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Extracellular Matrix Disassembly Regulation Of Keratinocyte Differentiation Proteolysis Involved In Cellular Protein Catabolic Process
Pathways			Endosomal/Vacuolar pathway Degradation of the extracellular matrix Activation of Matrix Metalloproteinases Trafficking and processing of endosomal TLR Assembly of collagen fibrils and other multimeric structures MHC class II antigen presentation RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Drugs			3-amino-5-phenylpentane 4-Methylpiperazin-1-Yl Carbonyl Group
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Hippocampal volume in normal cognition ( 29274321) Placental abruption ( 29884306) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma parathyroid hormone levels ( 30134803) Spatial memory ( 31596458) Sphingomyelin 24:0 levels ( 31560688)
Interacting Genes		24 interacting genes: ASPH BAAT CCDC180 CTSV FANCC FBP2 HRAS MAP2K1 MAPK12 MAPK3 MBP NANS PFKM PPP2CB PPP3R2 RANGAP1 SFRP4 SMAD1 SPARCL1 TBC1D2 TGFB1 TMEM129 XPA ZNF510	13 interacting genes: APC BMPR1A BRAF BUB1 CDKN2A CTNNA1 DCC DLC1 MLH1 MLH3 PDGFRL RB1 SRC
Entrez ID		5157	1515
HPRD ID		05206	04495
Ensembl ID		ENSG00000104213	ENSG00000136943
Uniprot IDs		Q15198	A0A024R141 B2R717 O60911
PDB IDs			1FH0 3H6S 3KFQ
Enriched GO Terms of Interacting Partners?
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