RAB6B and PMM1

Data Source:
BioGRID (two hybrid)

		RAB6B	PMM1
Description		RAB6B, member RAS oncogene family	phosphomannomutase 1
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endomembrane System Cytoplasmic Vesicle Presynapse	Cytosol Neuronal Cell Body
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin V Binding	Phosphomannomutase Activity Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi	Mannose Metabolic Process Protein N-linked Glycosylation GDP-mannose Biosynthetic Process Cellular Response To Leukemia Inhibitory Factor
Pathways		COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Synthesis of GDP-mannose
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245)	Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: ACVR1 BICD2 BMPR1B COG6 ERC1 KIF20A LNX2 MEOX2 PMM1 RABGAP1 RAP1GDS1 SH2B2 SMAD1 TGFBR1	5 interacting genes: CACNA1A MFHAS1 RAB6A RAB6B RCHY1
Entrez ID		51560	5372
HPRD ID		11474	03473
Ensembl ID		ENSG00000154917	ENSG00000100417
Uniprot IDs		Q9NRW1	A0A024R1U5 Q92871
PDB IDs		2E9S 2FE4 2FFQ	2FUC 2FUE 6CFR 6CFS 6CFT 6CFU 6CFV
Enriched GO Terms of Interacting Partners?
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