RAB6B and KIF20A

Data Source:
HPRD (two hybrid)

		RAB6B	KIF20A
Description		RAB6B, member RAS oncogene family	kinesin family member 20A
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endomembrane System Cytoplasmic Vesicle Presynapse	Nucleus Nucleoplasm Golgi Apparatus Spindle Kinesin Complex Microtubule Midbody Cleavage Furrow Intercellular Bridge
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin V Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Kinase Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi	Mitotic Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Protein Transport Regulation Of Cytokinesis Midbody Abscission
Pathways		COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Iron status biomarkers (total iron binding capacity) ( 28334935) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		14 interacting genes: ACVR1 BICD2 BMPR1B COG6 ERC1 KIF20A LNX2 MEOX2 PMM1 RABGAP1 RAP1GDS1 SH2B2 SMAD1 TGFBR1	6 interacting genes: CDC14A FAM214B LRRK1 RAB6A RAB6B ZRANB2
Entrez ID		51560	10112
HPRD ID		11474	09292
Ensembl ID		ENSG00000154917	ENSG00000112984
Uniprot IDs		Q9NRW1	O95235
PDB IDs		2E9S 2FE4 2FFQ	6YIP
Enriched GO Terms of Interacting Partners?
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