PPHLN1 and NAGK

Data Source:
BioGRID (two hybrid)

		PPHLN1	NAGK
Description		periphilin 1	N-acetylglucosamine kinase
Image
GO Annotations	Cellular Component	Nucleoplasm Chromosome Golgi Apparatus Cytosol	Cytosol Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity
	Biological Process	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly Protein Localization To Heterochromatin	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation
Pathways			Synthesis of UDP-N-acetyl-glucosamine
Drugs			N-Acetylglucosamine
Diseases
GWAS		Body size at age 10 ( 32376654) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Refractive error ( 32231278)	Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		25 interacting genes: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 ITGB1BP2 MTUS2 NAGK PAXIP1 PPL SEPTIN8 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM	33 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82
Entrez ID		51535	55577
HPRD ID		10488	08441
Ensembl ID		ENSG00000134283	ENSG00000124357
Uniprot IDs		Q8NEY8	A0A384N6G7 C9JEV6 Q9UJ70
PDB IDs		6SWG	2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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