PDE6D and RAB13

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		PDE6D	RAB13
Description		phosphodiesterase 6D	RAB13, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cilium Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Bicellular Tight Junction Synaptic Vesicle Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	GTPase Inhibitor Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Visual Perception Negative Regulation Of GTPase Activity Response To Stimulus	Vesicle Docking Involved In Exocytosis Protein Secretion Protein Kinase A Signaling Endosomal Transport Regulation Of Exocytosis Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Endothelial Cell Chemotaxis Post-translational Protein Modification Trans-Golgi Network To Recycling Endosome Transport Golgi Vesicle Fusion To Target Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier
Pathways		ARL13B-mediated ciliary trafficking of INPP5E RAS processing	Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Eating disorders (purging via substances) ( 23568457) Height ( 18391951)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: ARL15 ARL16 ARL2 ARL3 CDC42 CETN3 FAM219A GNAI1 GRK1 GRK7 HRAS OTP PTGIR RAB13 RAB18 RAB8A RAD23A RAP1A RAP2B RASA1 RHEB RHOA RHOB RND1 RPGR	10 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1
Entrez ID		5147	5872
HPRD ID		04056	04053
Ensembl ID		ENSG00000156973	ENSG00000143545
Uniprot IDs		B8ZZK5 O43924 Q6IB24	A0A087WWB9 P51153 Q504R6
PDB IDs		1KSG 1KSH 1KSJ 3T5G 3T5I 4JHP 4JV6 4JV8 4JVB 4JVF 5E80 5E8F 5F2U 5ML2 5ML3 5ML4 5ML6 5ML8 5NAL 5TAR 5TB5 5X72 5X73 5X74 5YAV 5YAW
Enriched GO Terms of Interacting Partners?
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