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CHAF1A and TRIB3
Data Source:
BioGRID
(two hybrid)
CHAF1A
TRIB3
Description
chromatin assembly factor 1 subunit A
tribbles pseudokinase 3
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Protein-containing Complex
CAF-1 Complex
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Molecular Function
Chromatin Binding
Protein Binding
Identical Protein Binding
Unfolded Protein Binding
Chromo Shadow Domain Binding
Transcription Corepressor Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Kinase Activity
Protein Kinase Binding
Mitogen-activated Protein Kinase Kinase Binding
Ubiquitin Protein Ligase Binding
Ubiquitin-protein Transferase Regulator Activity
Biological Process
DNA Replication
DNA Repair
Nucleosome Assembly
DNA Replication-dependent Nucleosome Assembly
Cell Cycle
Chromatin Assembly
Negative Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Regulation Of Autophagy
Regulation Of Glucose Transmembrane Transport
Regulation Of Lipid Metabolic Process
Positive Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Response To Endoplasmic Reticulum Stress
Regulation Of MAP Kinase Activity
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Protein Kinase B Signaling
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
PIP3 activates AKT signaling
Activation of AKT2
PPARA activates gene expression
Negative regulation of the PI3K/AKT network
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK1 (HRI) to heme deficiency
Drugs
Diseases
GWAS
Hemoglobin (
32888494
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red cell distribution width (
32888494
27863252
28957414
)
Information processing speed (
21130836
)
Logical memory (delayed recall) (
29274321
)
Logical memory (immediate recall) (
29274321
)
Interacting Genes
47 interacting genes:
ANP32A
ANP32B
ASF1A
ASF1B
BLM
CBX1
CBX5
CDC7
CDK2
CHAF1B
CREBBP
DBF4
DDX41
H3-4
H3C6
HMGB2
LZTR1
MBD1
MEI4
MSH6
NOTO
PABPC1
PAX6
PCBD2
PCNA
POU6F2
RBFOX2
REL
SERTAD1
SET
SPOP
STAT5B
SUMO1
SUMO2
SUMO3
TCERG1
TCF4
TRIB3
TRIM28
XRCC5
XRCC6
YWHAB
YWHAE
YWHAG
YWHAQ
ZNF408
ZNF620
99 interacting genes:
AKAP8L
AKT1
AKT2
APOBEC3A
APOBEC3C
APP
ARMC7
ATF4
BAG3
BCL6
BFSP2
BMPR2
C21orf58
C22orf39
CBX8
CHAF1A
CLCNKA
COPS6
CTAG1A
CTAG1B
DDIT3
DPPA3
DTX2
EEF1G
EFEMP2
EPHB6
EXOSC5
FAAP20
FAM161A
FAM90A1
FBXO7
GDF9
GIT1
GLIS3
GPATCH2L
GRB2
HAT1
HDAC4
HLA-B
HNRNPF
HOXB5
HOXC8
IL16
INCA1
INO80B
IRX6
KANK2
KAT5
KLHL38
KRT26
LENG1
LMO2
LMO3
MDFI
MISP
OIP5
OSTF1
PADI4
PARD6B
PCSK5
PITX2
PKNOX2
PML
PPP1R26
PPP1R32
PRKAB2
PRMT5
PRR19
PSMA3
RARA
RBM4
RBM48
RELA
RIDA
RPGRIP1
RPSA
SAMD11
SAXO1
SCNM1
SETDB1
SHFL
SNRPC
SPAG8
SPG21
SQSTM1
SUOX
TCF19
TEKT3
TEKT4
TLE5
TRIM55
TRIM63
TTC23
TWIST1
UBTD2
USP20
UTP23
ZNF417
ZNF587
Entrez ID
10036
57761
HPRD ID
03148
09836
Ensembl ID
ENSG00000167670
ENSG00000101255
Uniprot IDs
Q13111
B4DMM9
J3KR25
Q96RU7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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