REEP2 and TTPA

Data Source:
BioGRID (two hybrid)

		REEP2	TTPA
Description		receptor accessory protein 2	alpha tocopherol transfer protein
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Integral Component Of Plasma Membrane Membrane Endoplasmic Reticulum Tubular Network	Late Endosome Cytosol
	Molecular Function	Protein Binding Microtubule Binding Taste Receptor Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding
	Biological Process	Regulation Of Intracellular Transport Protein Transport Into Membrane Raft Sensory Perception Of Bitter Taste Sensory Perception Of Sweet Taste Endoplasmic Reticulum Tubular Network Organization	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer
Pathways		Olfactory Signaling Pathway	Vitamin E
Drugs
Diseases			Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS		Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) Schizophrenia ( 25056061)
Interacting Genes		24 interacting genes: BNIP3 C2CD2L CMTM5 CYP4F2 CYP4F22 ITGAM MS4A1 MUL1 NAT8 ORMDL3 RABAC1 SCD SFT2D2 SLC25A46 TMBIM6 TMEM120B TMEM208 TMEM239 TMEM31 TMEM42 TMEM60 TMX2 TTPA YIF1A	46 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52
Entrez ID		51308	7274
HPRD ID		16655	02685
Ensembl ID		ENSG00000132563	ENSG00000137561
Uniprot IDs		A8K3D2 Q9BRK0	P49638
PDB IDs			1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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