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REEP2 and MUL1
Data Source:
BioGRID
(two hybrid)
REEP2
MUL1
Description
receptor accessory protein 2
mitochondrial E3 ubiquitin protein ligase 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytoplasmic Microtubule
Integral Component Of Plasma Membrane
Membrane
Endoplasmic Reticulum Tubular Network
Mitochondrion
Peroxisome
Membrane
Axon
Integral Component Of Mitochondrial Outer Membrane
Neuronal Cell Body
Molecular Function
Protein Binding
Microtubule Binding
Taste Receptor Binding
P53 Binding
Ubiquitin-protein Transferase Activity
Protein Binding
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Regulation Of Intracellular Transport
Protein Transport Into Membrane Raft
Sensory Perception Of Bitter Taste
Sensory Perception Of Sweet Taste
Endoplasmic Reticulum Tubular Network Organization
Protein Polyubiquitination
Mitochondrial Fission
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of JUN Kinase Activity
Negative Regulation Of Mitochondrial Fusion
Regulation Of Mitochondrion Organization
Protein Ubiquitination
Protein Sumoylation
Negative Regulation Of Cell Growth
Protein Destabilization
Positive Regulation Of Protein Sumoylation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Innate Immune Response
Negative Regulation Of Defense Response To Virus By Host
Protein Stabilization
Mitochondrion Localization
Regulation Of Mitochondrial Membrane Potential
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Cellular Response To Exogenous DsRNA
Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of Mitochondrial Fission
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Dendrite Extension
Positive Regulation Of Autophagy Of Mitochondrion In Response To Mitochondrial Depolarization
Pathways
Olfactory Signaling Pathway
Ub-specific processing proteases
Drugs
Diseases
GWAS
Amyotrophic lateral sclerosis (C9orf72 mutation interaction) (
22959728
)
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
31043756
)
Bipolar I disorder (
31043756
)
Cerebrospinal AB1-42 levels in Alzheimer's disease dementia (
29274321
)
Schizophrenia (
25056061
)
Proportion of activated microglia (inferior temporal cortex) (
30679421
)
Interacting Genes
24 interacting genes:
BNIP3
C2CD2L
CMTM5
CYP4F2
CYP4F22
ITGAM
MS4A1
MUL1
NAT8
ORMDL3
RABAC1
SCD
SFT2D2
SLC25A46
TMBIM6
TMEM120B
TMEM208
TMEM239
TMEM31
TMEM42
TMEM60
TMX2
TTPA
YIF1A
34 interacting genes:
AKT1
APPBP2
CDC34
DNM1L
EHD1
HTRA2
KRTAP10-8
MAP3K7
RANGAP1
REEP2
STING1
SUMO1
TAP1
TP53
TP73
TRIM9
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2L3
UBE2L6
UBE2N
UBE2R2
UBE2U
UBE2V2
UBE2W
UBXN7
ULK1
Entrez ID
51308
79594
HPRD ID
16655
07799
Ensembl ID
ENSG00000132563
ENSG00000090432
Uniprot IDs
A8K3D2
Q9BRK0
A1PUM0
Q969V5
PDB IDs
6K2K
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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