KIR2DL4 and BPIFA1

Data Source:
BioGRID (two hybrid)

		KIR2DL4	BPIFA1
Description		killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4	BPI fold containing family A member 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Early Endosome Membrane	Extracellular Region Extracellular Space
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class Ib Receptor Activity	Molecular_function Protein Binding Lipid Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Cytokine Production Cellular Defense Response Signal Transduction Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Positive Regulation Of Cellular Senescence	Immune Response In Nasopharyngeal-associated Lymphoid Tissue Antimicrobial Humoral Response Antibacterial Humoral Response Innate Immune Response Regulation Of Liquid Surface Tension Multicellular Organismal Water Homeostasis Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Regulation Of Sodium Ion Transmembrane Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Antimicrobial peptides
Drugs
Diseases
GWAS		Objective response to lithium treatment ( 26503763)
Interacting Genes		9 interacting genes: BPIFA1 FCER1G FHL5 HLA-G INCA1 RBPMS RNF216 TIMMDC1 TRIP6	50 interacting genes: ALKBH4 COL8A1 CRYBA2 CSKMT DUSP21 ELK3 EML2 FAAP20 FAM222B GADD45GIP1 GCA HCK HNF1B HOXB9 HSFY1 HSFY2 INCA1 INIP KIR2DL4 KRT3 LNX1 MEIS2 MKRN3 MTIF3 NPAS2 NUP54 PATZ1 PEF1 PITX1 PPIH PRR35 PSMB1 RAMAC RSPH14 RTP5 RUSC1 SAMD11 SIRPB1 SNRNP25 TCF7L2 TEPSIN TFG TIAL1 TLE5 TLX3 UBQLN1 UBQLN2 UBQLN4 VPS25 ZNF765
Entrez ID		3805	51297
HPRD ID		16082	07594
Ensembl ID		ENSG00000189013	ENSG00000198183
Uniprot IDs		A0A0B4J1S6 A0A376A929 Q99706	Q9NP55
PDB IDs		3WYR	4KEG 4KGH 4KGO 4N4X 5I7J 5I7K 5I7L
Enriched GO Terms of Interacting Partners?
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