ADIPOR1 and DPH3

Data Source:
BioGRID (two hybrid)

		ADIPOR1	DPH3
Description		adiponectin receptor 1	diphthamide biosynthesis 3
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GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity	Protein Binding Metal Ion Binding
	Biological Process	Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of NIK/NF-kappaB Signaling	TRNA Wobble Uridine Modification Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways		AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity	Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494 27863252)
Interacting Genes		6 interacting genes: APPL1 DPH3 NAA20 NFKBIL1 STK11 TBXA2R	6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438
Entrez ID		51094	285381
HPRD ID		06402	16412
Ensembl ID		ENSG00000159346	ENSG00000154813
Uniprot IDs		Q96A54	Q96FX2
PDB IDs		5LXG 6KRZ 6KS0	2JR7
Enriched GO Terms of Interacting Partners?
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