ADIPOR1 and NFKBIL1

Data Source:
BioGRID (two hybrid)

		ADIPOR1	NFKBIL1
Description		adiponectin receptor 1	NFKB inhibitor like 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity	Protein Binding
	Biological Process	Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of NIK/NF-kappaB Signaling	I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Toll-like Receptor Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494 27863252)	Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 23128233) Eosinophil counts ( 32888494) Height ( 28552196) Hematocrit ( 32888494) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Neonatal lupus ( 20662065) Refractive error ( 32231278) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Type 2 diabetes ( 30054458) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: APPL1 DPH3 NAA20 NFKBIL1 STK11 TBXA2R	5 interacting genes: ADIPOR1 C2orf88 CASP10 CLEC18C NME7
Entrez ID		51094	4795
HPRD ID		06402	07043
Ensembl ID		ENSG00000159346	ENSG00000204498
Uniprot IDs		Q96A54	A0A0A0MRT5 A8K778 Q5STV6 Q9UBC1
PDB IDs		5LXG 6KRZ 6KS0
Enriched GO Terms of Interacting Partners?
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