DPH3 and SERGEF

		DPH3	SERGEF
Description		diphthamide biosynthesis 3	secretion regulating guanine nucleotide exchange factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	TRNA Wobble Uridine Modification Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Protein Secretion Positive Regulation Of Binding	Signal Transduction Negative Regulation Of Protein Secretion Regulation Of Catalytic Activity
Pathways		Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30643258) Body mass index ( 26426971)
Interacting Genes		6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438	8 interacting genes: DPH3 EXOC2 FOXH1 HGS KDM1A PITX1 PRMT6 SPAG8
Entrez ID		285381	26297
HPRD ID		16412	06926
Ensembl ID		ENSG00000154813	ENSG00000129158
Uniprot IDs		Q96FX2	A8K8C1 Q9UGK8
PDB IDs		2JR7
Enriched GO Terms of Interacting Partners?
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