LAP3 and ZYX

Data Source:
BioGRID (two hybrid)

		LAP3	ZYX
Description		leucine aminopeptidase 3	zyxin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Trans-Golgi Network Cytosol Focal Adhesion Midbody Extracellular Exosome	Stress Fiber Nucleus Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion Actin Cytoskeleton Phagocytic Vesicle
	Molecular Function	Aminopeptidase Activity Protein Binding Metalloexopeptidase Activity Manganese Ion Binding Metalloaminopeptidase Activity	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Proteolysis	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma
Pathways
Drugs		Leucine Phosphonic Acid (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid Zofenoprilat	Artenimol
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Blood protein levels ( 28240269) Monocyte percentage of white cells ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		12 interacting genes: APP BANP CBX3 CBX5 LIG4 MAPRE3 PIH1D2 PIK3R3 TAB1 USF1 ZNF76 ZYX	35 interacting genes: ACTN1 ATXN1 BSPRY CASS4 ENAH EVL HIPK3 IMP3 LAP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A QRICH1 RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384 ZNF512B
Entrez ID		51056	7791
HPRD ID		07516	03592
Ensembl ID		ENSG00000002549	ENSG00000159840
Uniprot IDs		P28838	Q15942 Q96AF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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