GLRX2 and ELF5

Data Source:
BioGRID (two hybrid)

		GLRX2	ELF5
Description		glutaredoxin 2	E74 like ETS transcription factor 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle	Chromatin Nucleus
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Glutathione Metabolic Process Apoptotic Process Aging Response To Temperature Stimulus Regulation Of Signal Transduction Response To Organic Substance Protein Phosphopantetheinylation Electron Transport Chain Cell Differentiation DNA Protection Response To Hydrogen Peroxide Cell Redox Homeostasis Response To Redox State Cellular Response To Superoxide	Regulation Of Transcription By RNA Polymerase II Cell Differentiation
Pathways
Drugs		Glutathione
Diseases
GWAS		Blood protein levels ( 29875488)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Blood protein levels ( 28240269) Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: DCXR ELF5 FBXO7 TXNRD1	9 interacting genes: ACTR2 FRZB GLRX2 NFE2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4
Entrez ID		51022	2001
HPRD ID		12112	05525
Ensembl ID		ENSG00000023572	ENSG00000135374
Uniprot IDs		Q9NS18	A0A087X1W9 A8K443 Q9UKW6
PDB IDs		2CQ9 2FLS 2HT9	1WWX
Enriched GO Terms of Interacting Partners?
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