GLRX2 and DCXR

Data Source:
BioGRID (two hybrid)

		GLRX2	DCXR
Description		glutaredoxin 2	dicarbonyl and L-xylulose reductase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle	Nucleus Cytoplasmic Microtubule Plasma Membrane Microvillus Brush Border Extracellular Exosome
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	Carbonyl Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Identical Protein Binding L-xylulose Reductase (NAD+) Activity L-xylulose Reductase (NADP+) Activity
	Biological Process	Regulation Of Transcription, DNA-templated Glutathione Metabolic Process Apoptotic Process Aging Response To Temperature Stimulus Regulation Of Signal Transduction Response To Organic Substance Protein Phosphopantetheinylation Electron Transport Chain Cell Differentiation DNA Protection Response To Hydrogen Peroxide Cell Redox Homeostasis Response To Redox State Cellular Response To Superoxide	Xylulose Metabolic Process Glucose Metabolic Process NADP Metabolic Process Glucuronate Catabolic Process To Xylulose 5-phosphate D-xylose Metabolic Process
Pathways			Formation of xylulose-5-phosphate Essential pentosuria
Drugs		Glutathione	Dihydrogenphosphate Nicotinamide adenine dinucleotide phosphate
Diseases			Pentosuria
GWAS		Blood protein levels ( 29875488)	Refractive error ( 32231278)
Interacting Genes		4 interacting genes: DCXR ELF5 FBXO7 TXNRD1	3 interacting genes: APP CRADD GLRX2
Entrez ID		51022	51181
HPRD ID		12112	16320
Ensembl ID		ENSG00000023572	ENSG00000169738
Uniprot IDs		Q9NS18	A0A384NY14 Q7Z4W1
PDB IDs		2CQ9 2FLS 2HT9	1PR9 1WNT 3D3W
Enriched GO Terms of Interacting Partners?
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