MAGEA1 and PCGF6

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		MAGEA1	PCGF6
Description		MAGE family member A1	polycomb group ring finger 6
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GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564	26 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RING1 RNF2 SS18L1 TRIM14 TRIM55 TRIM63 TULP3 UBE2D3 UBE2U USP2 USP21
Entrez ID		4100	84108
HPRD ID		02059	07427
Ensembl ID		ENSG00000198681	ENSG00000156374
Uniprot IDs		P43355	Q9BYE7
PDB IDs		1W72 3BO8	2DJB
Enriched GO Terms of Interacting Partners?
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