MAGEA1 and TRIM31

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		MAGEA1	TRIM31
Description		MAGE family member A1	tripartite motif containing 31
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Histone Deacetylase Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Anger ( 24489884) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Beta-2 microglubulin plasma levels ( 23417110) Blood protein levels ( 28240269) Estimated glomerular filtration rate in diabetes ( 31451708) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Isovolumetric relaxation time ( 28394258) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 27863252) Neuroticism ( 29255261) Prostate cancer ( 25217961) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
Interacting Genes		25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564	22 interacting genes: CCT6A EID3 IKBKG MAGEA1 MAGEA2B MKRN3 MNAT1 NLRP3 NSMCE4A TRAF2 TRIM23 TRIM27 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2K UBE2L3 UBE2W USP7 ZSCAN1
Entrez ID		4100	11074
HPRD ID		02059	10281
Ensembl ID		ENSG00000198681	ENSG00000204616
Uniprot IDs		P43355	Q2L6J1 Q9BZY9
PDB IDs		1W72 3BO8	2YSJ 2YSL
Enriched GO Terms of Interacting Partners?
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