PAX7 and MAGOHB

Data Source:
BioGRID (two hybrid)

		PAX7	MAGOHB
Description		paired box 7	mago homolog B, exon junction complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Exon-exon Junction Complex Neuronal Cell Body U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Anatomical Structure Morphogenesis Negative Regulation Of Apoptotic Process Anatomical Structure Development	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Alveolar rhabdomyosarcoma
GWAS		Body mass index ( 23669352) Cleft lip with or without cleft palate ( 28054174) Cortical surface area (visual PC2) ( 32198502) Knee osteoarthritis ( 28916551) Nonsyndromic cleft lip with cleft palate ( 28232668) Orofacial clefts ( 22863734 28054174) Percentage gas trapping ( 26030696) Response to amphetamines ( 22952603) Urate levels in lean individuals ( 25811787)
Interacting Genes		11 interacting genes: C1orf109 CIB1 CSNK2A1 CT55 FHL1 HIRA HOMER3 KRTAP19-7 MAGOHB NEDD4 TCAP	73 interacting genes: ADAMTSL4 AMOTL2 BEND7 C18orf54 CALCOCO2 CARD10 CCDC102B CCDC106 CCDC33 DVL2 DVL3 EFHC2 FHL5 FXR1 GNPDA2 GOLGA2 GPANK1 HMG20A HSF2BP IHO1 IKZF1 IKZF3 INCA1 KRT40 KRT75 KRTAP1-1 KRTAP13-2 MID2 NDUFB7 PARD6B PAX7 PBX4 PKP2 PRPH PRPSAP1 PTPN21 RBAK RBM8A RBMX REL RUNDC3A SNW1 SPATA6 SPDYE4 STX11 TADA2A TCF4 TERF2 TERF2IP THAP7 TLE5 TRA2A TRA2B TRIM27 TRIM42 YWHAG ZBTB10 ZBTB42 ZFP14 ZFYVE1 ZNF19 ZNF250 ZNF398 ZNF426 ZNF438 ZNF446 ZNF449 ZNF547 ZNF566 ZNF57 ZNF620 ZNF774 ZNF835
Entrez ID		5081	55110
HPRD ID		01331	08544
Ensembl ID		ENSG00000009709	ENSG00000111196
Uniprot IDs		P23759	A0A023T6R1 F5H6P7 Q96A72
PDB IDs			5XJC 5YZG 6ICZ 6QDV
Enriched GO Terms of Interacting Partners?
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