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PRDX1 and GAPDH
Data Source:
BioGRID
(biochemical, two hybrid)
HPRD
(two hybrid)
PRDX1
GAPDH
Description
peroxiredoxin 1
glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Melanosome
Extracellular Exosome
Nucleus
Cytoplasm
Lipid Droplet
Cytosol
Plasma Membrane
Microtubule Cytoskeleton
Membrane
Nuclear Membrane
Vesicle
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
RNA Binding
Peroxidase Activity
Protein Binding
Thioredoxin Peroxidase Activity
Cadherin Binding
Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity
Protein Binding
Microtubule Binding
Aspartic-type Endopeptidase Inhibitor Activity
Peptidyl-cysteine S-nitrosylase Activity
Identical Protein Binding
NADP Binding
NAD Binding
Disordered Domain Specific Binding
Biological Process
Skeletal System Development
Retina Homeostasis
Response To Oxidative Stress
Cell Population Proliferation
Removal Of Superoxide Radicals
Natural Killer Cell Activation
Cellular Response To Stress
Cellular Response To Oxidative Stress
Hydrogen Peroxide Catabolic Process
Leukocyte Activation
Cell Redox Homeostasis
Microtubule Cytoskeleton Organization
Positive Regulation Of Cytokine Production
Gluconeogenesis
Glycolytic Process
Negative Regulation Of Endopeptidase Activity
Regulation Of Macroautophagy
Negative Regulation Of Translation
Killing Of Cells Of Other Organism
Peptidyl-cysteine S-trans-nitrosylation
Protein Stabilization
Defense Response To Fungus
Neuron Apoptotic Process
Killing By Host Of Symbiont Cells
Canonical Glycolysis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Interferon-gamma
Pathways
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Glycolysis
Gluconeogenesis
Drugs
Zinc
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
NADH
Adenosine-5-Diphosphoribose
Thionicotinamide-Adenine-Dinucleotide
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Xanthinol
Copper
Artenimol
Diseases
GWAS
Blood protein levels (
28240269
)
Body mass index (
26426971
)
Hemoglobin (
32888494
)
Blood protein levels (
30072576
)
Interacting Genes
29 interacting genes:
ABL1
ADH5
ADRB2
AXIN2
BTRC
CALM1
CCR4
CLEC4G
EGFR
GAPDH
IRF3
LUC7L
MTRNR2L1
MYC
MYD88
PPP2R1A
PPP2R1B
PRDX4
PTEN
PTGER4
SESN1
SESN2
SH2D1B
SMARCD1
SNCA
TERF1
UBE3A
VHL
YWHAQ
84 interacting genes:
ACD
ACTB
ACTC1
ANXA1
ANXA7
APP
AR
ARL15
ATN1
ATXN1
BID
BPGM
BTBD2
CAMK1
CAMK2B
CAMK4
CDKN1A
CDKN2A
CHP1
DUX4
DYNLL1
EGFR
ERBB2
FBXO7
FKBP6
GADD45A
GAS7
GOT2
GRIA2
GRM1
HES1
HNF4G
HSPB2
HTT
ITGB5
KARS1
KAT5
KCNE3
LAMA4
LAMTOR5
LIG4
LINC01554
MAPK1
MTNR1A
MYOC
NFYC
NR1H4
OSMR
OSTF1
PAFAH1B3
PCDHA4
PCNA
PDIA2
PGK1
PLD2
POT1
POU2F2
PPM1E
PRDX1
PRKCI
PRPF40A
PSEN1
PSMD11
PTPRF
RAB2A
RBM5
RPA2
RXFP4
S100A6
SERPINB9
SIAH1
SIRT1
SLC2A1
SLC2A4
SMN1
SNCA
SUMO4
TERF1
TINF2
TK1
TPPP
USP25
YWHAE
YWHAQ
Entrez ID
5052
2597
HPRD ID
01458
00713
Ensembl ID
ENSG00000117450
ENSG00000111640
Uniprot IDs
A0A384NPQ2
Q06830
P04406
V9HVZ4
PDB IDs
2RII
3HY2
4XCS
1U8F
1ZNQ
2FEH
3GPD
4WNC
4WNI
6ADE
6IQ6
6YND
6YNE
6YNF
6YNH
Enriched GO Terms of Interacting Partners
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