SLC22A18 and RNF167

Data Source:
BioGRID (enzymatic study)

		SLC22A18	RNF167
Description		solute carrier family 22 member 18	ring finger protein 167
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane	Cytoplasm Endomembrane System Integral Component Of Membrane
	Molecular Function	Protein Binding Symporter Activity Transmembrane Transporter Activity Ubiquitin Protein Ligase Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Excretion Organic Cation Transport Xenobiotic Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle
Pathways		Organic cation transport Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Bilirubin levels ( 19414484) Calcium levels ( 20705733) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Malaria ( 31844061) Total bilirubin levels ( 29403010)	Blood metabolite levels ( 24816252) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		5 interacting genes: HSD17B11 NKX3-1 RNF167 TLCD4 TMX2	17 interacting genes: ACTA1 AFG3L2 ATP2A1 CAPN3 MYH7 SLC22A18 SUMO1 TTN UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2K UBE2N UBE2W
Entrez ID		5002	26001
HPRD ID		04024	15261
Ensembl ID		ENSG00000110628	ENSG00000108523
Uniprot IDs		E9PRM7 Q96BI1	I3L0L6 Q9H6Y7
PDB IDs
Enriched GO Terms of Interacting Partners?
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