SLC22A18 and TLCD4

Data Source:
BioGRID (two hybrid)

		SLC22A18	TLCD4
Description		solute carrier family 22 member 18	TLC domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane	Cellular_component Endoplasmic Reticulum Integral Component Of Membrane
	Molecular Function	Protein Binding Symporter Activity Transmembrane Transporter Activity Ubiquitin Protein Ligase Binding	Molecular_function Protein Binding
	Biological Process	Excretion Organic Cation Transport Xenobiotic Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Biological_process Lipid Homeostasis
Pathways		Organic cation transport Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Bilirubin levels ( 19414484) Calcium levels ( 20705733) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Malaria ( 31844061) Total bilirubin levels ( 29403010)
Interacting Genes		5 interacting genes: HSD17B11 NKX3-1 RNF167 TLCD4 TMX2	71 interacting genes: ADGRB3 ADGRE2 ARV1 ATP13A1 BNIP3 CACNG1 CCDC167 CDIPT CHPT1 CLCN7 CLEC7A CMTM5 COMT CTXN3 CXCL16 CYP4F2 CYP4F22 DHRSX EBP EMC6 EMP1 ERG28 FA2H FDFT1 FXYD6 FXYD6-FXYD2 GJB2 GOSR2 GYPA HMOX1 IGFBP5 KRT1 LNPEP MS4A13 MYG1 NAT8 NDUFA3 NINJ1 NKG7 ORMDL1 PMP22 PRAF2 PRRT2 REEP6 SCAMP5 SCD SEC22A SEC22B SERP1 SFXN1 SFXN3 SLC22A18 SLC41A1 SMAGP STATH STX12 SYNDIG1 SYNJ2BP TIMM23 TMEM115 TMEM120B TMEM19 TMEM229B TMEM237 TMEM60 TMIE TVP23B UBE2J1 VEZT YIPF1 YIPF4
Entrez ID		5002	148534
HPRD ID		04024	08110
Ensembl ID		ENSG00000110628	ENSG00000152078
Uniprot IDs		E9PRM7 Q96BI1	Q96MV1
PDB IDs
Enriched GO Terms of Interacting Partners?
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