ODC1 and BAAT

Data Source:
BioGRID (two hybrid)

		ODC1	BAAT
Description		ornithine decarboxylase 1	bile acid-CoA:amino acid N-acyltransferase
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Ornithine Decarboxylase Activity Protein Binding Protein Homodimerization Activity	Protein Binding Palmitoyl-CoA Hydrolase Activity N-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Choloyl-CoA Hydrolase Activity Acyl-CoA Hydrolase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Acyl-CoA Hydrolase Activity Long-chain Acyl-CoA Hydrolase Activity Very Long Chain Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Response To Virus Putrescine Biosynthetic Process From Ornithine Regulation Of Protein Catabolic Process	Liver Development Bile Acid Conjugation Glycine Metabolic Process Protein Targeting To Peroxisome Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Taurine Metabolic Process Animal Organ Regeneration
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Peroxisomal protein import Peroxisomal protein import
Drugs		Pyridoxal phosphate Spermine Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine	Glycine
Diseases			Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS
Interacting Genes		18 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 OAZ3 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510	24 interacting genes: APC AURKA BCL10 BUB1 CDKN2A CTNNA1 DLC1 ERBB2 GOLGA8DP GOLGA8EP GOLGA8F MCC MLH1 MLH3 MUTYH ODC1 PDGFRL PEX5 PTPRJ RAD54B RB1 SLC7A11 SMAD4 SRC
Entrez ID		4953	570
HPRD ID		01324	08376
Ensembl ID		ENSG00000115758	ENSG00000136881
Uniprot IDs		B4DXF8 P11926	Q14032
PDB IDs		1D7K 2ON3 2OO0 4ZGY 5BWA
Enriched GO Terms of Interacting Partners?
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