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BAAT and MUTYH
Data Source:
BioGRID
(two hybrid)
BAAT
MUTYH
Description
bile acid-CoA:amino acid N-acyltransferase
mutY DNA glycosylase
Image
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Peroxisomal Matrix
Cytosol
Nucleus
Nucleoplasm
Mitochondrion
Molecular Function
Protein Binding
Palmitoyl-CoA Hydrolase Activity
N-acyltransferase Activity
Transferase Activity, Transferring Acyl Groups
Choloyl-CoA Hydrolase Activity
Acyl-CoA Hydrolase Activity
Glycine N-choloyltransferase Activity
Carboxylic Ester Hydrolase Activity
Medium-chain Acyl-CoA Hydrolase Activity
Long-chain Acyl-CoA Hydrolase Activity
Very Long Chain Acyl-CoA Hydrolase Activity
Myristoyl-CoA Hydrolase Activity
Purine-specific Mismatch Base Pair DNA N-glycosylase Activity
Protein Binding
DNA N-glycosylase Activity
Oxidized Purine DNA Binding
MutLalpha Complex Binding
MutLbeta Complex Binding
MutSalpha Complex Binding
MutSbeta Complex Binding
8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity
Adenine/guanine Mispair Binding
Metal Ion Binding
4 Iron, 4 Sulfur Cluster Binding
Biological Process
Liver Development
Bile Acid Conjugation
Glycine Metabolic Process
Protein Targeting To Peroxisome
Fatty Acid Metabolic Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Bile Acid Metabolic Process
Taurine Metabolic Process
Animal Organ Regeneration
DNA Repair
Base-excision Repair
Mismatch Repair
Depurination
Pathways
Recycling of bile acids and salts
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Peroxisomal protein import
Peroxisomal protein import
Drugs
Glycine
Diseases
Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
Familial adenomatous polyposis
GWAS
Composite immunoglobulin trait (IgA/IgM) (
28628107
)
Periventricular white matter hyperintensities (
32517579
)
Interacting Genes
24 interacting genes:
APC
AURKA
BCL10
BUB1
CDKN2A
CTNNA1
DLC1
ERBB2
GOLGA8DP
GOLGA8EP
GOLGA8F
MCC
MLH1
MLH3
MUTYH
ODC1
PDGFRL
PEX5
PTPRJ
RAD54B
RB1
SLC7A11
SMAD4
SRC
19 interacting genes:
AGTRAP
APEX1
BAAT
CYLC2
FANCC
HRAS
LMNA
LRSAM1
MSANTD3
MSH6
PCNA
RPA1
RPA4
SEC61B
SIRT6
SMAD1
TDRD7
TSTD2
XPA
Entrez ID
570
4595
HPRD ID
08376
05380
Ensembl ID
ENSG00000136881
ENSG00000132781
Uniprot IDs
Q14032
D3DPZ6
E5KP25
E5KP26
E5KP27
E5KP28
E9PM53
Q9UIF7
PDB IDs
1X51
3N5N
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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