ODC1 and STX17

Data Source:
BioGRID (two hybrid)

		ODC1	STX17
Description		ornithine decarboxylase 1	syntaxin 17
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GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Autophagosome Membrane Mitochondrion Lysosomal Membrane Autophagosome Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle Smooth Endoplasmic Reticulum Membrane HOPS Complex SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	Ornithine Decarboxylase Activity Protein Binding Protein Homodimerization Activity	SNARE Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Phosphatase Binding
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Response To Virus Putrescine Biosynthetic Process From Ornithine Regulation Of Protein Catabolic Process	Intracellular Protein Transport Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Golgi Organization Autophagosome Membrane Docking Protein Localization To Phagophore Assembly Site Vesicle Docking Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Autophagosome Maturation
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	COPII-mediated vesicle transport
Drugs		Pyridoxal phosphate Spermine Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS			Alopecia areata ( 20596022) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)
Interacting Genes		18 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 OAZ3 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510	23 interacting genes: ATG14 AURKA BUB1 CDH1 CTNNA1 DLC1 EGFR KRAS MAP2K4 MIS18A MLH1 MLH3 MSH2 NRAS ODC1 PTPN12 PTPN2 RB1 SMAD4 SNAP29 SRC STK11 TLR2
Entrez ID		4953	55014
HPRD ID		01324	05013
Ensembl ID		ENSG00000115758	ENSG00000136874
Uniprot IDs		B4DXF8 P11926	P56962
PDB IDs		1D7K 2ON3 2OO0 4ZGY 5BWA	4WY4 7BV4 7BV6
Enriched GO Terms of Interacting Partners?
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