ODC1 and NANS

Data Source:
BioGRID (two hybrid)

		ODC1	NANS
Description		ornithine decarboxylase 1	N-acetylneuraminate synthase
Image
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Ornithine Decarboxylase Activity Protein Binding Protein Homodimerization Activity	N-acylneuraminate Cytidylyltransferase Activity N-acylneuraminate-9-phosphate Synthase Activity N-acetylneuraminate Synthase Activity
	Biological Process	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Response To Virus Putrescine Biosynthetic Process From Ornithine Regulation Of Protein Catabolic Process	CMP-N-acetylneuraminate Biosynthetic Process Carbohydrate Biosynthetic Process Glycosylation
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Sialic acid metabolism
Drugs		Pyridoxal phosphate Spermine Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
Diseases
GWAS			Alopecia areata ( 25608926) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		18 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 OAZ3 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510	19 interacting genes: APC AURKA BCL10 BUB1 CDH1 CTNNA1 EGFR FBXO7 FBXW7 FLCN MCC MLH3 MSH6 ODC1 PDGFRL PTPRJ SRC STK11 TLR2
Entrez ID		4953	54187
HPRD ID		01324	07285
Ensembl ID		ENSG00000115758	ENSG00000095380
Uniprot IDs		B4DXF8 P11926	Q9NR45
PDB IDs		1D7K 2ON3 2OO0 4ZGY 5BWA	1WVO
Enriched GO Terms of Interacting Partners?
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