NTS and CPE

Data Source:
HPRD (in vivo)

		NTS	CPE
Description		neurotensin	carboxypeptidase E
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Transport Vesicle Intracellular Membrane-bounded Organelle Axon Terminus	Extracellular Space Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome
	Molecular Function	Neuropeptide Hormone Activity Protein Binding Receptor Ligand Activity Neuropeptide Receptor Binding	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Insulin processing
Drugs			Insulin human Insulin pork
Diseases
GWAS		Metabolite levels ( 23823483)	Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		10 interacting genes: ACE2 ARRB2 CPE MEP1A MFF NLN NTSR1 NTSR2 PREP SORT1	18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A
Entrez ID		4922	1363
HPRD ID		08878	00272
Ensembl ID		ENSG00000133636	ENSG00000109472
Uniprot IDs		P30990 Q6FH20	A0A384N679 P16870
PDB IDs		2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ 6UP7
Enriched GO Terms of Interacting Partners?
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