NTS and NTSR1

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		NTS	NTSR1
Description		neurotensin	neurotensin receptor 1
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GO Annotations	Cellular Component	Extracellular Region Transport Vesicle Intracellular Membrane-bounded Organelle Axon Terminus	Mitochondrion Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Cell Surface Symmetric Synapse Terminal Bouton Dendritic Spine Dendritic Shaft Perikaryon Membrane Raft
	Molecular Function	Neuropeptide Hormone Activity Protein Binding Receptor Ligand Activity Neuropeptide Receptor Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Neurotensin Receptor Activity Identical Protein Binding Protein-containing Complex Binding Protein N-terminus Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway	Temperature Homeostasis Negative Regulation Of Systemic Arterial Blood Pressure Regulation Of Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Learning Adult Locomotory Behavior Positive Regulation Of Glutamate Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Response To Lipid Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Respiratory Gaseous Exchange Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Sensory Perception Of Pain Positive Regulation Of Inositol Phosphate Biosynthetic Process D-aspartate Import Across Plasma Membrane Inositol Phosphate Catabolic Process Positive Regulation Of Arachidonic Acid Secretion Positive Regulation Of Inhibitory Postsynaptic Potential L-glutamate Import Across Plasma Membrane Regulation Of Action Potential Positive Regulation Of Cation Channel Activity
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: ACE2 ARRB2 CPE MEP1A MFF NLN NTSR1 NTSR2 PREP SORT1	2 interacting genes: ARRB2 NTS
Entrez ID		4922	4923
HPRD ID		08878	01218
Ensembl ID		ENSG00000133636	ENSG00000101188
Uniprot IDs		P30990 Q6FH20	P30989
PDB IDs		2LNE 2LNF 2LNG 2LYW 2OYV 2OYW 3F6K 4PO7 5LUZ 6UP7	2LYW 6OS9 6OSA 6PWC 6UP7
Enriched GO Terms of Interacting Partners?
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