CPE and GAST

Data Source:
HPRD (in vivo)

		CPE	GAST
Description		carboxypeptidase E	gastrin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding	Hormone Activity Protein Binding
	Biological Process	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Protein Localization To Membrane	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food
Pathways		Insulin processing	G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK
Drugs		Insulin human Insulin pork	Oxetacaine
Diseases
GWAS		Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		18 interacting genes: BDNF CCK CHD3 CNTNAP2 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A	24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B
Entrez ID		1363	2520
HPRD ID		00272	00671
Ensembl ID		ENSG00000109472	ENSG00000184502
Uniprot IDs		A0A384N679 P16870	A0A0E3VY36 P01350
PDB IDs			5WRJ
Enriched GO Terms of Interacting Partners?
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