ATP1B3 and TMEM98

Data Source:
BioGRID (two hybrid)

		ATP1B3	TMEM98
Description		ATPase Na+/K+ transporting subunit beta 3	transmembrane protein 98
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Sperm Flagellum Melanosome Extracellular Exosome	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	ATPase Activator Activity Protein Binding Protein-macromolecule Adaptor Activity ATPase Binding	Protein Binding
	Biological Process	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Leukocyte Migration Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Negative Regulation Of Protein Processing Negative Regulation Of Myelination T-helper 1 Cell Differentiation Negative Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Protein Localization To Nucleus
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 27841878) Red cell distribution width ( 32888494 27863252 28957414) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196) White blood cell count ( 32888494)	Body mass index ( 28552196) Myopia ( 27182965) Platelet distribution width ( 32888494) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		13 interacting genes: BAALC BARD1 BRCA1 CTXN3 NLRP3 PAXIP1 PEA15 SMAGP STOM TMEM98 TRIM14 UPF2 USP4	10 interacting genes: ATP1B3 GJB1 GOLM1 HTR6 MUC1 RABEPK SGTA STOM SUSD3 TNNT1
Entrez ID		483	26022
HPRD ID		03521	13171
Ensembl ID		ENSG00000069849	ENSG00000006042
Uniprot IDs		P54709	Q9Y2Y6
PDB IDs
Enriched GO Terms of Interacting Partners?
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