TMEM98 and ATP1B3

Data Source:
BioGRID (two hybrid)

		TMEM98	ATP1B3
Description		transmembrane protein 98	ATPase Na+/K+ transporting subunit beta 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Sperm Flagellum Melanosome Extracellular Exosome
	Molecular Function	Protein Binding	ATPase Activator Activity Protein Binding Protein-macromolecule Adaptor Activity ATPase Binding
	Biological Process	Negative Regulation Of Protein Processing Negative Regulation Of Myelination T-helper 1 Cell Differentiation Negative Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Protein Localization To Nucleus	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Leukocyte Migration Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways			Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Body mass index ( 28552196) Myopia ( 27182965) Platelet distribution width ( 32888494) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Blond vs. brown/black hair color ( 30531825) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 27841878) Red cell distribution width ( 32888494 27863252 28957414) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196) White blood cell count ( 32888494)
Interacting Genes		10 interacting genes: ATP1B3 GJB1 GOLM1 HTR6 MUC1 RABEPK SGTA STOM SUSD3 TNNT1	13 interacting genes: BAALC BARD1 BRCA1 CTXN3 NLRP3 PAXIP1 PEA15 SMAGP STOM TMEM98 TRIM14 UPF2 USP4
Entrez ID		26022	483
HPRD ID		13171	03521
Ensembl ID		ENSG00000006042	ENSG00000069849
Uniprot IDs		Q9Y2Y6	P54709
PDB IDs
Enriched GO Terms of Interacting Partners?
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